Ten years after the horrific events of Werewolf in a Women's Prison, the penitentiary has a new warden with a thirst for blood. Young American Liz (Victoria De Mare) travels to the the third world country of Campuna to gather her sisters remains, who mysteriously passed in jail. However, anyone who dies in Campuna State Prison comes back to life under warden Drago better known as Count Dracula (Robert Rhine).

When the reckless actions of an out-of-control LAPD officer get his partner killed in a deadly hostage situation, he gets suspended from the police force and heads to Mexico to face off against corrupt cops.